Surgical Applications & Probes

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The Navigator system is used in radio-guided surgical procedures, primarily for lymphatic mapping and tumor localization. Over the last several decades, procedures such as sentinel lymph node mapping, first in melanoma, and more recently in breast, have become a gold standard of care among general surgeons and surgical oncologists.

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Radio-guided surgical techniques using radio-pharmaceuticals for uptake by a number of different tumor sites, has been effective in the localization of other diseases, such as parathyroid adenomas and recurrent cancer. Most recently, MIS (Minimally Invasive Surgical) procedures, such as VATS, have proven to be effective in the localization of small occult tumors in the lung. This procedure allows for surgeons to stage cancer much earlier than the “wait-and-see” approach.

Dilon Technologies manufactures a diverse family of intra-operative probes, designed specifically for each of these procedures.

Sentinel Lymph Node Biopsy (SLNB), also referred to as Intraoperative Lymphatic Mapping (ILM), involves the localization of the lymph node that is first in the lymph node chain to receive lymphatic drainage from a primary tumor site.

 

Radioisotope localization facilitates rapid, precise identification of targeted nodule, minimizing resected tissue, while providing feedback to the surgeon of clean margins, prior to the pathology report. This radio-guided solution is a safe and effective alternative to blue dye or Kopans needles, which are typically unreliable.

 

In a parathyroid adenoma procedure, the patient is injected intravenously with Tc-99 sestamibi several hours prior to surgery. Once in the OR, a small incision is made and the thyroid gland is exposed. The probe is then placed on the thyroid gland in the center of the neck, the readings from this area constituting background counts.

 

These probes are most commonly used in radio-guided, minimally invasive surgical (MIS) procedures for gynecological, urological, colorectal, and gastrointestinal malignancies. Whether used for lymphatic mapping, or tumor localization, these probes are both efficient and reliable.

 

The most common reason for cancer recurrence is failure to detect and remove cancer cells in the tumor area, most frequently occurring after previous surgical resections. These tumors are not visibly discernable, nor are they palpable. The PET isotope, FDG-18, is most often used to localize these occult tumor cells.